Reye's syndrome | Easy Pediatrics
The prognosis depends on the severity of central nervous system depression. Previously, mortality was as high as 90%. Today, ICP monitoring and, consequently, early treatment of increased ICP, along with other treatment measures, have cut mortality to about 20%. Death is usually a result of cerebral edema or respiratory arrest. Comatose patients who survive may have residual brain damage. With Reye’s syndrome, damaged hepatic mitochondria disrupt the urea cycle, which normally changes ammonia to urea for its excretion from the body. This results in hyperammonemia, hypoglycemia, and an increase in serum short-chain fatty acids, leading to encephalopathy. Simultaneously, fatty infiltration is found in renal tubular cells, neuronal tissue, and muscle tissue, including the heart. After the initial viral infection, a brief recovery period follows when the child doesn’t seem seriously ill. A few days later, he develops intractable vomiting, lethargy, rapidly changing mental status (mild to severe agitation, confusion, irritability, delirium), hyperactive reflexes, and rising blood pressure, respiratory rate, and pulse rate. To decrease intracranial pressure (ICP) and brain edema, give I.V. fluids at two-thirds of the maintenance dose. Also give an osmotic diuretic or furosemide. To treat hypoprothrombinemia, give vitamin K; if vitamin K proves unsuccessful, give fresh frozen plasma. Monitor serum ammonia and blood glu-cose levels and plasma osmolality every 4 to 8 hours to check progress.
Intracranial Pressure Monitoring - Bookshelf
Intracranial pressure monitoring
Intracranial Pressure and Brain Monitoring XIII, Mechanisms and Treatment
86 short papers originating from the 13th International Symposium on Intracranial Pressure and Brain Monitoring held in July 2007 in San Francisco present ...Intracranial pressure and brain monitoring XII
88 short papers originating from the 12th International Symposium on Intracranial Pressure and Brain Monitoring held in August 2004 in Hong Kong present ...Problems of intracranial pressure in childhood
1951), continuous ICP monitoring was not carried out as part of routine ... When continuous ICP monitoring is carried out, systemic blood pressure (SBP) ...Intracranial pressure and neuromonitoring in brain injury, proceedings of the Tenth International ICP Symposium, Williamsburg, May 25-29, 1997
The fact that a majority of IPC are discontinued within a week, points to their role in short term ICP monitoring in the absence of a reliable neurological ...Knowledge Base Directory
Intracranial pressure monitoring: MedlinePlus Medical ...
Intracranial pressure monitoring uses a device, placed inside the head, which senses the pressure inside the skull and sends its measurements to a recording device. ...
Intracranial pressure monitoring - Wikipedia, the free ...
The monitoring of intracranial pressure is used in treating severe traumatic brain injury patients. This process is called intracranial pressure monitoring. ...
Intracranial pressure monitoring - Overview
Intracranial pressure monitoring - Overview, Intracranial pressure monitoring uses a device, pl...
Intracranial Pressure Monitoring
1.1 Definition: The primary goals of intracranial pressure (ICP) monitoring are. identification of intracranial pressure trends and evaluation of therapeutic ...
Saint Thomas Health Services - Health Information ...
There are three ways to monitor pressure in the brain cavity (intracranial pressure) ... Raised intracranial pressure means that both nervous system (neural) and blood vessel ...